Annuit cœptis is one of two mottos (the other being Novus ordo seclorum) on the reverse side of the Great Seal of the United States. Taken from the Latin words annuo (nod, approve) and cœpta (beginnings, undertakings), it is literally translated as "He approves (or has approved) [our] undertaking(s)". In 1782, Congress appointed a design artist, William Barton of Philadelphia, to bring a proposal for the national seal.
Epicardium describes the outer layer of heart tissue (from Greek; epi- outer, cardium heart). When considered as a part of the pericardium, it is the inner layer, or visceral pericardium, continuous with the serous layer. Its largest constituent is connective tissue and functions as a protective layer. The visceral pericardium apparently produces the pericardial fluid, which lubricates motion between the inner and outer layers of the pericardium.