Phenylalanine hydroxylase is an enzyme which catalyses the reaction responsible for the addition of a hydroxyl group to the end of the 6-carbon aromatic ring of phenylalanine, such that it becomes tyrosine: Image:L-phenylalanine-skeletal. png|Phenylalanine Image:L-tyrosine-skeletal. png|Tyrosine Phenylalanine hydroxylase is the rate-limiting enzyme of the metabolic pathway which degrades excess phenylalanine. The other substrates in the reaction are molecular oxygen and tetrahydrobiopterin.
In the field of molecular biology, BK channels, also called Maxi-K or slo1, are ion channels which conduct potassium (K) ions through cell membranes. These channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentrations of intracellular Ca.
Clathrin is a protein which plays a major role in the formation of coated vesicles. Clathrin was first isolated and named by Barbara Pearse in 1975. It forms a triskelion shape which is composed of three clathrin heavy chains and three light chains. When the triskelion interact they form a polyhedral lattice which surrounds the vesicle.
Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, are a family of enzymes which damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. Lysozyme is abundant in a number of secretions, such as tears, saliva, human milk and mucus.
alpha-2-Macroglobulin, also known as α2-macroglobulin and abbreviated as α2M and A2M, is a large plasma protein found in the blood. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis.
Von Willebrand factor (vWF) is a blood glycoprotein involved in hemostasis. It is deficient or defective in von Willebrand disease and is involved in a large number of other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic-uremic syndrome.
Insulin-like growth factor 1 (IGF-1), which was once called somatomedin C, is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults.
Keratin 1 is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants of bullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected.
Keratin, type II cytoskeletal 7 is a protein that in humans is encoded by the KRT7 gene. Keratin 7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.
Pizzicato is a playing technique that involves plucking the strings of a string instrument. The exact technique varies somewhat depending on the type of stringed instrument. On bowed string instruments it is a method of playing by plucking the strings with the fingers, rather than using the bow. This produces a very different sound from bowing, short and percussive rather than sustained.
Avondale is a city in Maricopa County, Arizona, USA. According to 2008 Census Bureau estimates, the population of the city is 81,299. Avondale is the home of Phoenix International Raceway, a famous auto racing facility. Westview High School, La Joya Community High School, and Agua Fria High School are large high schools in Avondale.
Roermond is a city, a municipality, and a diocese in the southeastern part of the Netherlands. The city of Roermond is a historically important town, on the lower Roer at the east bank of the Meuse river. It received city rights in 1231. Roermond town centre has been designated as a conservation area. Through the centuries the town has filled the role of commercial centre, principal town in the duchy of Guelders and since 1559 it has served as the seat of the Roman Catholic Diocese of Roermond.
For Heaven's Sake is a 1926 comedy silent film starring Harold Lloyd. It was made just before one of Lloyd's most critically-praised films today, The Kid Brother. Commercially, it was one of Lloyd's most successful films and the 12th highest-grossing film of the silent era, pulling in $2,600,000.