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likeorhate
Last updated
2013-05-21 14:43:32
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O 2,4-dinitrofenol (DNP'), C6H4N2O5, é um veneno metabólico celular. Desacopla a fosforilação oxidativa através do transporte de protões através da membrana mitocondrial, levando a um rápido consumo de energia sem a geração de ATP. Os dinitrofenóis são uma classe de compostos, dos quais existem seis membros, isômeros de posição, que não ocorrem naturalmente e são todos sintéticos. More information...

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  • Benzphetamine (Didrex) is an anorectic drug marketed under this brand in the USA by Pharmacia. Benzphetamine is used as a short term adjunct in management of exogenous obesity. It is closely related to amphetamine.
    http://en.wikipedia.org/wiki/File:Benzphetamine.png
  • Orlistat (marketed as a prescription under the trade name Xenical by Roche in most countries, or over-the-counter as Alli by GlaxoSmithKline) in the United States, also known as tetrahydrolipstatin, is a drug designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. It is intended for use in conjunction with a physician-supervised reduced-calorie diet.
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  • Sibutramine, usually available as sibutramine hydrochloride monohydrate, is an orally administered agent for the treatment of obesity, as an appetite suppressant. Serious concerns are being expressed about its safety and has been suspended from use in the UK and EU. It is also under review by the FDA and the European Medicines Agency. It is a centrally-acting serotonin-norepinephrine reuptake inhibitor structurally related to amphetamines, although its mechanism of action is distinct.
    http://commons.wikipedia.org/wiki/File:Sibutramine3d.png
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    http://en.wikipedia.org/wiki/File:Phendimetrazine.jpg
  • Oleoyl-estrone (OE) is a fatty acid ester of estrone. It is a naturally circulating hormone in animals including humans. It was first reported in 1996 to cause a body fat loss effect in rats in the International Journal of Obesity and Related Metabolic Disorders. The animal research has all been conducted by the Nitrogen-Obesity Research Group of the University of Barcelona.
    http://en.wikipedia.org/wiki/File:Oleoylestrone.png
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  • Tesofensine (NS2330) is a serotonin-noradrenaline-dopamine reuptake inhibitor from the phenyltropane family of drugs, which is being developed for the treatment of obesity. The right to develop and market tesofensine is held by NeuroSearch, a Danish pharmaceutical company.
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  • Redux was the commercial name of a weight-loss drug based on dexfenfluramine hydrochloride. This drug was retired from the market in 1997 when a study suggested it could be related to heart problems.

 

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