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Uma Sequência Alu é uma porção curta de DNA, originalmente caracterizada pela acção da endonuclease de restrição Alu. Sequências Alu de diferentes tipos ocorrem em grandes quantidades nos genomas de primatas. Aliás, sequências Alu são o elemento móvel mais abundante no genoma humano. Elas são derivadas do 7SL RNA, um componente da signal recognition particle. O evento, quando uma cópia de 7SL RNA se tornou um precursor da sequência Alu, teve lugar no genoma do ancestral dos Supraprimatas. More information...

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  • Microsatellites, Simple Sequence Repeats (SSRs), or tandem repeats, are repeating sequences of 1-6 base pairs of DNA. Microsatellites are typically neutral and co-dominant. They are used as molecular markers in genetics, for kinship, population and other studies. They can also be used to study gene duplication or deletion.
  • A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration. Its name is derived from the Greek nouns telos (τἐλος) "end" and merοs "part". Russian theorist Alexei Olovnikov was the first to recognize (1971) the problem of how chromosomes could replicate right to the tip, as such was impossible with replication in a 5' to 3' direction.
    http://commons.wikipedia.org/wiki/File:Parallel_telomere_quadruple.png
  • An inverted repeat (or IR) is a sequence of nucleotides that is the reversed complement of another sequence further downstream. For example, 5'---GACTGC.... GCAGTC---3'. When no nucleotides intervene between the sequence and its downstream complement, it is called a palindrome. Inverted repeats define the boundaries in transposons. Inverted repeats also indicate regions capable of self-complementary base pairing (regions within a single sequence which can base pair with each other).
  • An STR multiplex system is used to quickly identify specific short tandem repeats. STR polymorphisms are genetic markers that may be used to identify a DNA sequence. The FBI uses 13 specific STR loci in their database. These may be used in many areas of genetics in addition to their legal uses. One can think of a STR Multiplex System as collection of certain specific STRs which are positionally conserved on a target genome. Hence these can be used as markers.
  • Tandem repeats occur in DNA when a pattern of two or more nucleotides is repeated and the repetitions are directly adjacent to each other.
  • A short tandem repeat (STR) in DNA occurs when a pattern of two or more nucleotides are repeated and the repeated sequences are directly adjacent to each other. The pattern can range in length from 2 to 16 base pairs (bp) (for example n in a genomic region) and is typically in the non-coding intron region. A short tandem repeat polymorphism (STRP) occurs when homologous STR loci differ in the number of repeats between individuals.
    http://en.wikipedia.org/wiki/File:Str_profile.jpg
  • A minisatellite is a section of DNA that consists of a short series of bases 10–60 bp. These occur at more than 1000 locations in the human genome. Some minisatellites contain a central (or "core") sequence of letters “GGGCAGGANG” (where N can be any base) or more generally a strand bias with purines on one strand and pyrimidines on the other. It has been proposed that this sequence per se encourages chromosomes to swap DNA.
  • Satellite DNA consists of highly repetitive DNA, and is so called because repetitions of a short DNA sequence tend to produce a different frequency of the nucleotides adenine, cytosine, guanine and thymine, and thus have a different density from bulk DNA - such that they form a second or 'satellite' band when genomic DNA is separated on a density gradient.
  • In the study of DNA sequences, one can distinguish two main types of repeated sequence: Tandem repeats: Satellite DNA, Minisatellite, Microsatellite; Interspersed repeats: SINEs (Short Interspersed Nuclear Elements), LINEs (Long Interspersed Nuclear Elements). The majority of LINEs are LINE-1 and the majority of SINEs are Alu's. In prokaryotes, CRISPR are arrays of alternating repeats and spacers.
  • A Variable Number Tandem Repeat (or VNTR) is a location in a genome where a short nucleotide sequence is organized as a tandem repeat. These can be found on many chromosomes, and often show variations in length between individuals. Each variant acts as an inherited allele, allowing them to be used for personal or parental identification. Their analysis is useful in genetics and biology research, forensics, and DNA fingerprinting.
    http://commons.wikipedia.org/wiki/File:Codis_profile.jpg

 

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  • Bread is a staple food prepared by cooking a dough of flour and water and possibly more ingredients. Doughs are usually baked, but in some cuisines breads are steamed, fried, or baked on an unoiled skillet. It may be leavened or unleavened. Salt, fat and leavening agents such as yeast and baking soda are common ingredients, though bread may contain other ingredients, such as milk, egg, sugar, spice, fruit, vegetables, nuts or seeds.
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  • A screw terminal is a type of electrical connector where a wire is clamped down to metal by a screw. The wire is sometimes just stripped of electrical insulation at the end, and is bent in a U or J shape to fit around the shaft of the screw. Alternatively, a lug can be crimped onto the end of the wire to protect it. Setscrews are also used, as in a luster terminal or lustre terminal, but lugs will not fit into them. For both lugs and bare wire, the screw is tightened for a secure connection.
    http://en.wikipedia.org/wiki/File:Terminal_Blocks_01CJC.png

 
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