This is about synthesizers or synthesizer controllers that can be played like guitars. For keyboard synthesizers that are held like guitars, see keytar. A guitar synthesizer (also guitar/synthesizer, guitar/synth, g-synth, synth guitar, guitar-synth, or guitar synth) is any one of a number of musical instrument systems that allow a guitar player to play synthesizers.
The Roland GR-500, manufactured by Roland Corporation, was the first commercially available guitar synthesizer. The synthesizer module included Bass, Solo Synth, and String sounds based on previous Orchestral and analog mono-synths from Roland. There are a number of sliders to adjust the VCO, VCF, VCA, and LFO sections, but no memory to store your edits. The synth module is controlled by a "highly modified" guitar.